The first isolation and structure identifications of prednisone and prednisolone were done in 1950 by Arthur Nobile .    The first commercially feasible synthesis of prednisone was carried out in 1955 in the laboratories of Schering Corporation, which later became Schering-Plough Corporation , by Arthur Nobile and coworkers.  They discovered that cortisone could be microbiologically oxidized to prednisone by the bacterium Corynebacterium simplex. The same process was used to prepare prednisolone from hydrocortisone . 
Serrapeptase is found in the Biomedic Labs Signature products Serra RX80 , Serra RX260 (Newest & Highest potency serrapeptase)and Serracor NK , a specialty serrapeptase & nattokinase formula. In these products Biomedic Labs uses a unique process of enterically coated serrapeptase powder unlike any others, called BPPS so that it passes through the stomach unharmed and can be effectively absorbed into the body through the small intestine where it is then absorbed into the bloodstream. This method of enteric coating is expensive but allows for the highest absorption and effectiveness of any serrapeptase product on the market.
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