Oxandrolone is most certainly a hepatotoxic steroid. It does not carry the strongest level of hepatotoxicity among anabolic steroids, but it is stronger than most. This is due to it being a C17-aa anabolic steroid. All C17-aa steroids are hepatic, but the level of toxicity varies greatly between them. Due to this steroid’s strong hepatotoxicity, this is why total use must be limited (see administration section).
Due to use, those who supplement with Anadrol will find their liver enzyme values increase. An increase in values is not a sign of damage but rather a sign of stress that can lead to damage if responsible practices are not followed and the stress is allowed to remain. Proper dosing and duration of use protocols are imperative when it comes to this steroid. Further, it is important the individual avoids excess alcohol consumption when supplementing with this steroid due to the liver stress such consumption will cause. In fact, most will find avoiding all alcohol to be best during use. If this is a problem and you are supplementing for the purpose of performance enhancement remember there is nothing on earth that is as anti-performance as alcohol. Those who supplement are also encouraged to limit their use of Over the Counter (OTC) medications. Many OTC medications carry strong hepatic natures, and the added stress can be extensive when coupled with Anadrol. Use should be limited to when only absolutely needed. If these rules can be followed, once use is discontinued liver enzyme values will return to normal and no damage will be done. As a final note, Anadrol should not be used if the liver is unhealthy.
I have found SD to be a far superior alternative to Anadrol, as it is not only at least equally effective for increasing muscle fullness (more so in many instances), but it does not carry with it the same risk of sub-q water retention. Pure, properly compounded SD (20-30 mg/day) results in a hard, dense, and dry appearance, which works synergistically with the other orals mentioned above to ensure you come in as full and conditioned as possible. However, as with all steroids, I suggest experimenting with it prior to the competition in order to gauge its effects on your own body, as a small percentage of individuals do not respond as well to this drug. Another option is Dimethazine. This oral is closely related to SD (it is 2 SD molecules attached by an azine bond) and provides visually identical effects at a slightly higher dosage (45 mg/day).
This subject would not be complete if we did not touch on the ability of AAS to incite fat loss. There is much speculation in this arena, as many of the drugs BB’rs utilize during prep were never clinically studied in human beings, leaving us with the sometimes job of discerning which drugs work best. While anecdotal evidence has served us well over the years, the presence of a clinical study offers further confirmation that we have been on the right rack (or not). Fortunately, two of our most commonly used pre-contest drugs have been proven capable of increasing the rate of fat loss. These are testosterone and trenbolone. Trenbolone in particular has consistently demonstrated impressive results, which is why I almost always recommend its inclusion as a core injectable. Some individuals choose shy away from tren due to its high side effect profile, but for those who can tolerate the drug, few, if any drugs will offer an equal number of benefits during contest prep.
There has also been talk of terminating the use of all injectables at 2 weeks out. Advocates of this method claim that it is necessary for achieving optimal condition. The logic used to sustain this assertion is that injectables, by way of intramuscular delivery, result in a minor degree of water retention via increased inflammation. It is true that even slightly invasive procedures, such as an injection, will produce an inflammatory effect, but the level of inflammation necessary to result in a visible response is unlikely to occur when using non-irritating, sterile steroid preparations, especially when delivered with a 25 g. syringe or smaller. If anyone is worried about this, one can simply discontinue all injections at 3-4 days out. By the time the comp rolls around, the inflammation will no longer be present.