Metabolic/Endocrine: Decreased glucose tolerance (see PRECAUTIONS ), increased serum levels of low-density lipoproteins and decreased levels of high-density lipoproteins (see PRECAUTIONS , Laboratory Tests ), increased creatine and creatinine excretion, increased serum levels of creatinine phosphokinase (CPK). Reversible changes in liver function tests also occur, including increased Bromsulphalein (BSP) retention and increases in serum bilirubin , glutamic-oxaloacetic transaminase ( SGOT ), and alkaline phosphatase .
Of all the Anadrol side effects, liver toxicity (hepatotoxicity) is of the greatest concern. Most oral steroids are alkylated, which means they’ve been specially designed in such a way that they will still be useful to your body once they’ve been processed by your liver. To reduce risk, it’s vital to use supplements like milk thistle, which serve as protections against potential damage; and drink plenty of water. It’s also important to use the lowest possible dose that provides you with benefits, and to adjust your cycle length based on your dose.
Effects of steroid withdrawal are known to emulate and kick start many other medical complications as well. Weakness, loss of appetite, fatigue, nausea, weight loss, vomiting, diarrhea (further resulting in liquid and electrolyte complications), as well as abdominal pain are some of the most common effects that steroid withdrawal is often associated with. Constant decrease in blood pressure which simultaneously causes a person to faint or causes fits and dizziness are other complications the steroid use can cause.
Blood sugar levels are known to have dropped in many people who consume steroids. In women, menstrual changes have been reported widely. Muscle and joint pains, fever, changes in mentality, as well as elevation in calcium levels have been reported in some cases. Gastrointestinal contractions decrease dramatically which may ultimately lead to the swelling of the intestine .